Frequently Asked Questions About Frozen Eggs
Freezing eggs can be helpful for women who want to maintain their fertility in the future.
– Women who want to delay their fertility for reasons such as continuing their education, career and personal goals can benefit from freezing their eggs.
– Women with cancer.
* When is the best time for me to freeze my egg?
A woman in her early years of fertility feels confident about the time of family formation, and having a sexual partner that she also declares her readiness to have a child, and the strength and physical ability that is suitable for pregnancy can help a woman achieve fertility and Help fertilize. Unfortunately, some women face barriers to becoming pregnant, and some are reluctant to wait until they are able to maintain fertility.
How does egg freezing work?
Although it has been shown that freezing sperm and embryos is easy, eggs are the largest cells in the body that contain large amounts of water. When cells freeze, nail shape crystals can damage cells, and over the years, we have found that we need to dehydrate the eggs and get their water, and before the cell freezes, to protect the cell and prevent it. Formation of antifreeze ice crystals Replace water inside the cell. And we’ve found that since the eggshells harden during freezing. Sperm must be injected into the egg through a needle to fertilize the egg, which is called ICSI injection into the sperm cytoplasm.
The eggs are frozen in two ways, either by the method of nuclear freezing or by the method of rapid freezing called VITRIFICATION. Currently, we use the vitrification method for all eggs.
What is involved in freezing the egg?
In order to get an egg to freeze, the patient must be treated with hormone injections. The only difference is that after the egg is taken, before the eggs melt; Fertilize, are transferred into the uterus as an embryo, frozen for a period of time.
It takes about 4-6 weeks to complete the freezing cycles, which is consistent with the early stages of IVF, which includes 2-4 weeks of hormone injections and the use of birth control pills to eliminate the effects of natural hormones (this is the case in emergencies like before. Cancer treatment may not be considered)
۱۰-۱۴ days of hormone injection to stimulate the ovaries and mature several eggs at the same time
When the eggs are properly mature, they take a needle into the ovaries under vaginal ultrasound and harvest the mature eggs. This operation is performed under intravenous anesthesia and is not painful. The eggs freeze immediately. When the patient is ready to become pregnant, which can be several years later, the eggs melt and are injected with a fertile sperm and then transferred into the uterus as an embryo.
How long do eggs stay frozen?
In fertility, we freeze eggs in a similar way to freezing embryos. The degree of freezing we use to freeze eggs is 196 degrees centigrade. In a case of embryos frozen for 10 years, we are sure that long-term storage of frozen eggs will not reduce the quality of fertility, according to scientific evidence based on our experience with pregnant embryos.
How many eggs need to be stored to achieve fertility?
According to preliminary data from our studies and other studies, 75% of ovulation and 75% of fertilization in women are predictable by the age of 38, so if 10 eggs are frozen, 7 of them are expected to remain thawed. And 5 to 6 of them are expected to become fertile and become embryos, and usually 3-4 embryos are transferred into the uterus of women up to 38 years old. Therefore, it is recommended that 10 eggs be kept for each attempt at pregnancy. In most women, 38 or under 38 years of age, 10 to 20 eggs are expected to be obtained in each cycle.
What can I do if I am over 38?
Expectations for a pregnancy from frozen eggs depend on the woman’s age at the time of freezing her eggs and do not depend on when the woman goes for pregnancy. People are younger According to statistics, the number of pregnancies reported from frozen eggs in women over 38 is very low. This decrease is mostly due to the cessation of freezing of eggs at a younger age and the return of a relatively small number of women who use frozen eggs for pregnancy. Feminine pregnancies have been reported in women who were over the age of 40 or older at the time of ovulation. Also, in women up to 43 years of age, pregnancy is routinely performed using frozen embryos. With more research on egg freezing, we may be able to achieve this level of pregnancy using this method in the future. However, we do not know whether eggs obtained from women over the age of 40 respond similarly to the phenomenon of freezing, as do women over the age of 40 or under the age of 40.
Does freezing cause problems?
According to statistics, 5,000 babies are born through frozen eggs. According to a large published study of more than 900 children born through frozen eggs, the rate of congenital malformations increased compared to the general population not seen.
In 2014, a new study found that the number of pregnancy problems in frozen fetuses did not increase. More than 300,000 babies around the world have been born through frozen embryos from the egg-laying technique through slow freezing. And no increase in birth defects has been seen, although this data is reassuring, but further follow-up to ensure this is needed to prove that babies born through frozen eggs are naturally fertilized in terms of birth defects similar to those of fertilized infants.
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